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HighlightsIsosorbide MononitrateIsosorbide mononitrate is used for the prevention of angina. It can be used to decrease the frequency and severity of anginal (chest pain) episodes and to reduce the need for sublingual (taken under the tongue) nitroglycerin. The pain of coronary heart disease (angina) usually occurs when the heart requires more blood and oxygen than its blood vessels supplying the heart can deliver. The demand for oxygen can be reduced and pain prevented in one of two ways. First, by dilating the veins and allowing more blood to 'pool.' This reduces the amount of blood returning to the heart and hence the heart''s work and need for oxygen. Second, by dilating the arteries of the body and reducing the pressure within the arteries. This reduces the pressure that the heart has to pump against and hence the Heart''s work and need for oxygen. Isosorbide mononitrate reduces angina by dilating both the veins and the arteries.
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