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This medication is used to improve the symptoms of a certain blood flow problem in the legs/arms (intermittent claudication due to occlusive artery disease). Pentoxifylline can decrease the muscle aching/pain/cramps with exercise, including walking, that occur with intermittent claudication. Pentoxifylline belongs to a class of drugs known as hemorrheologic agents. It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (e.g., during exercise).OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used for decreased blood flow to the brain (cerebrovascular insufficiency), to improve blood flow problems in chronic heart failure, and to treat kidney problems from diabetes.How to use Trental OralTake this medication by mouth with food, usually 3 times daily or as directed by your doctor. Do not crush or chew the tablets. Doing so can destroy the long action of the drug and may increase side effects.Dosage is based on your medical condition, kidney function, and response to therapy.Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Do not stop this medication without your doctor's permission. Improvement in symptoms can occur in 2-4 weeks, but it may take up to 8 weeks to get the full benefit.Inform your doctor if your condition persists or worsens (e.g., muscle cramps/pain/aching do not improve or worsen).Trental Oral is used to treat the following:Peripheral Vascular Disease
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