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The combination of irbesartan and hydrochlorothiazide is used to treat high blood pressure. Irbesartan is in a class of medications called angiotensin II antagonists. It works by blocking the action of certain natural chemicals that tighten the blood vessels, making blood flow more smoothly. Hydrochlorothiazide is in a class of medications called diuretics ('water pills'). It works by causing the the kidneys to get rid of unneeded water and salt from the body into the urine.The combination of irbesartan and hydrochlorothiazide comes as a tablet to take by mouth. It is usually taken once a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take irbesartan and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Irbesartan and hydrochlorothiazide controls high blood pressure but does not cure it. It may take 2 to 4 weeks before you feel the full benefit of irbesartan and hydrochlorothiazide. Continue to take irbesartan and hydrochlorothiazide even if you feel well. Do not stop taking irbesartan and hydrochlorothiazide without talking to your doctor.
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