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HighlightsMetforminOral antidiabetic agent. This medicine is known as a biguanide which is indicated for non-insulin dependent (type 2) diabetes. The mode of action works mainly by inhibiting glucose production and reducing it''s absorption in the gut, hence lowering the blood sugar levels in diabetics. Metformin is the drug of choice in overweight patients in whom strict dieting has been unsuccessful or has failed to control diabetes. Hypoglycaemia (low blood sugar levels) is not a problem with this medicine, and it has a lower incidence of weight gain compared with other oral antidiabetic agents (e.g. sulphonylureas).
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