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Lisinopril is used to treat elevated blood pressure and heart failure. Lisinopril is an angiotensin converting enzyme (ACE) inhibitor. Angiotensin is a chemical that is made by the body continuously. It narrows blood vessels and thereby maintains (elevates) blood pressure. When the enzyme is blocked by lisinopril, angiotensin cannot be converted into its active form. As a result, blood pressure falls. Lisinopril should be taken at doses specifically directed by the physician. Lisinopril can be taken with or without food. Lisinopril should be taken at the same time each day to maintain consistent blood levels. Lisinopril should not be taken within two hours of taking an antacid since the antacid binds lisinopril and prevents its absorption. Lisinopril is often tapered when discontinuing.
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