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Felodipine is used to treat high blood pressure. It may be used alone or in combination with other agents. Felodipine also is used to treat patients with angina and is being studied in patients with congestive heart failure. Felodipine is an oral calcium- channel blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers in the DHP class include nifedipine (Procardia, Adalat), amlodipine (Norvasc), nisoldipine (Sular), nicardipine (Cardene), and isradipine (Dynacirc). Calcium is necessary for muscle cells to contract. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Felodipine has little or no effect on the muscles of veins or the heart .
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